Is allopurinol safe for ckd patients

by V Kannuthurai 2024 Cited by 6Studies have shown that allopurinol can be used safely to reduce SU levels in patients with CKD. While patients on ULT in this study did have a statistically

More CKD patients achieved a target uric acid level in studies where the allopurinol dose was titrated to effect as compared with those studies in which patients were given renally adjusted or untitrated allopurinol doses. Conclusions: Studies evaluating allopurinol use in patients with CKD have reported inconsistent findings relative to safety

by YJ Oh 2024 Cited by 3Febuxostat is an effective and safe uric acid lowering drug in allopurinol-intolerant patients with advanced CKD.

This study suggests that allopurinol therapy has a mortality benefit in patients with gout and moderate-to-severe CKD.

Patients with chronic kidney disease (CKD) are more likely to develop hyperuricemia and gout. Allopurinol and febuxostat are the most commonly used urate-lowering therapies with established safety and efficacy in CKD patients. The objective of the systematic review is to assess the long-term renal outcomes of allopurinol compared with febuxostat in patients with hyperuricemia and CKD or kidney

This study suggests that allopurinol therapy has a mortality benefit in patients with gout and moderate-to-severe CKD.

by F Saliba 2024colchicine, may carry too much adverse risk for a particular patient. The Studies show allopurinol can safely reduce serum urate in CKD. However

Allopurinol: Currently recommended as first-line therapy even in patients with moderate-to-severe CKD, allopurinol should be initiated at a

by YL Peng 2024 Cited by 23Febuxostat was associated with greater reduction in SUA level than allopurinol in patients with CKD. However, febuxostat and allopurinol